antitumor model - PMC

Michael C Brown, Georgia M Beasley, Zachary P McKay, Yuanfan Yang, Annick Desjardins, Dina M Randazzo, Daniel Landi, David M Ashley, Darell D Bigner, Smita K Nair, Matthias Gromeier

J Immunother Cancer. 2023; 11(4): e006463. Published online 2023 Apr 18. doi: 10.1136/jitc-2022-006463

PMCID:: PMC10124325

Article PDF–3.9M

Select item 75956735.

Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain

Lijia Pan, Litong Nie, Sheng Yao, Aiwei Bi, Yang Ye, Yeming Wu, Zhen Tan, Zhixiang Wu

Int J Mol Med. 2020 Dec; 46(6): 2137–2149. Published online 2020 Oct 6. doi: 10.3892/ijmm.2020.4745

PMCID:: PMC7595673

Article PDF–2.2M

Select item 88192866.

LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo

Yingqiang Liu, Mengzhen Lai, Shan Li, Yanan Wang, Fang Feng, Tao Zhang, Linjiang Tong, Mengge Zhang, Hao Chen, Yi Chen, Peiran Song, Yan Li, Gang Bai, Yi Ning, Haotian Tang, Yan Fang, Yi Chen, Xiaoyun Lu, Meiyu Geng, Ke Ding, Ker Yu, Hua Xie, Jian Ding

Cancer Sci. 2022 Feb; 113(2): 709–720. Published online 2021 Dec 16. doi: 10.1111/cas.15229

PMCID:: PMC8819286

Article PDF–1.8M

Select item 49577667.

Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity

Barbara A. Fox, Kiah L. Sanders, Leah M. Rommereim, Rebekah B. Guevara, David J. Bzik

PLoS Genet. 2016 Jul; 12(7): e1006189. Published online 2016 Jul 22. doi: 10.1371/journal.pgen.1006189

PMCID:: PMC4957766

Article PDF–3.1M

Select item 71103588.

Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile

Anne V. Yagolovich, Artem A. Artykov, Tatiana A. Karmakova, Maria S. Vorontsova, Andrey A. Pankratov, Alexander A. Andreev-Andrievsky, Dmitry A. Dolgikh, Mikhail P. Kirpichnikov, Marine E. Gasparian

Transl Oncol. 2020 Apr; 13(4): 100762. Published online 2020 Mar 27. doi: 10.1016/j.tranon.2020.100762

PMCID:: PMC7110358

Article PDF–2.8M

Select item 104596159.

Smart Targeted Delivery Systems for Enhancing Antitumor Therapy of Active Ingredients in Traditional Chinese Medicine

Chenglong Kang, Jianwen Wang, Ruotong Li, Jianing Gong, Kuanrong Wang, Yuxin Wang, Zhenghua Wang, Ruzhe He, Fengyun Li

Molecules. 2023 Aug; 28(16): 5955. Published online 2023 Aug 8. doi: 10.3390/molecules28165955

PMCID:: PMC10459615

Article PDF–6.3M

Select item 1006844310.

Liposome-Encapsulated Eribulin Shows Enhanced Antitumor Activity over Eribulin for Combination Therapy with Anti–PD-1 Antibody

Yuki Niwa, Keito Adachi, Kimiyo Tabata, Ryoga Ishida, Koichiro Hotta, Tomomi Ishida, Yuji Mano, Yoichi Ozawa, Yukinori Minoshima, Yasuhiro Funahashi, Taro Semba

Mol Cancer Ther. 2023 Apr 3; 22(4): 499–510. Published online 2023 Jan 24. doi: 10.1158/1535-7163.MCT-22-0475

PMCID:: PMC10068443

Article PDF–20M

Select item 1043699411.

Bacteria-based immunotherapy for cancer: a systematic review of preclinical studies

Min Zhou, Yucheng Tang, Wenjie Xu, Xinyan Hao, Yongjiang Li, Si Huang, Daxiong Xiang, Junyong Wu

Front Immunol. 2023; 14: 1140463. Published online 2023 Aug 3. doi: 10.3389/fimmu.2023.1140463

PMCID:: PMC10436994

Article PDF–4.3M

Select item 477584312.

DW10075, a novel selective and small-molecule inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo

Meng-yuan Li, Yong-cong Lv, Lin-jiang Tong, Ting Peng, Rong Qu, Tao Zhang, Yi-ming Sun, Yi Chen, Li-xin Wei, Mei-yu Geng, Wen-hu Duan, Hua Xie, Jian Ding

Acta Pharmacol Sin. 2016 Mar; 37(3): 398–407. Published online 2016 Jan 25. doi: 10.1038/aps.2015.117

PMCID:: PMC4775843

Article PDF–2.5M

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Autophagy, ferroptosis, pyroptosis, and necroptosis in tumor immunotherapy

Weitong Gao, Xueying Wang, Yang Zhou, Xueqian Wang, Yan Yu

Signal Transduct Target Ther. 2022; 7: 196. Published online 2022 Jun 20. doi: 10.1038/s41392-022-01046-3

PMCID:: PMC9208265

Article PDF–3.6M

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

Hirokazu Taniguchi, Rebecca Caeser, Shweta S. Chavan, Yingqian A. Zhan, Andrew Chow, Parvathy Manoj, Fathema Uddin, Hidenori Kitai, Rui Qu, Omar Hayatt, Nisargbhai S. Shah, Álvaro Quintanal Villalonga, Viola Allaj, Evelyn M. Nguyen, Joseph Chan, Adam O. Michel, Hiroshi Mukae, Elisa de Stanchina, Charles M. Rudin, Triparna Sen

Cell Rep. Author manuscript; available in PMC 2022 Sep 7.

Published in final edited form as: Cell Rep. 2022 May 17; 39(7): 110814. doi: 10.1016/j.celrep.2022.110814

PMCID:: PMC9449677

Article PDF–2.4M

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Combination Treatment of Topical Imiquimod Plus Anti-PD-1 Antibody Exerts Significantly Potent Antitumor Effect

Kazumasa Oya, Yoshiyuki Nakamura, Zhu Zhenjie, Ryota Tanaka, Naoko Okiyama, Yuki Ichimura, Yosuke Ishitsuka, Akimasa Saito, Noriko Kubota, Rei Watanabe, Hideaki Tahara, Manabu Fujimoto, Yasuhiro Fujisawa

Cancers (Basel) 2021 Aug; 13(16): 3948. Published online 2021 Aug 5. doi: 10.3390/cancers13163948

PMCID:: PMC8391905

Article PDF–3.6M

Select item 1065463616.

Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity

Alyson J. Smith, Robert E. Thurman, Weiping Zeng, Bryan Grogan, Sasha Lucas, Guadalupe Gutierrez, Ryan A. Heiser, Serena W. Wo, Amber Blackmarr, Scott Peterson, Shyra J. Gardai

Front Immunol. 2023; 14: 1280986. Published online 2023 Nov 1. doi: 10.3389/fimmu.2023.1280986

PMCID:: PMC10654636

Article PDF–9.3M

Select item 1037265417.

IL-7R licenses a population of epigenetically poised memory CD8⁺ T cells with superior antitumor efficacy that are critical for melanoma memory

Goran Micevic, Andrew Daniels, Karine Flem-Karlsen, Koonam Park, Ronan Talty, Meaghan McGeary, Haris Mirza, Holly N. Blackburn, Esen Sefik, Julie F. Cheung, Noah I. Hornick, Lilach Aizenbud, Nikhil S. Joshi, Harriet Kluger, Akiko Iwasaki, Marcus W. Bosenberg, Richard A. Flavell

Proc Natl Acad Sci U S A. 2023 Jul 25; 120(30): e2304319120. Published online 2023 Jul 17. doi: 10.1073/pnas.2304319120

PMCID:: PMC10372654

Article PDF–5.8M

Select item 975285518.

Non-coding RNA-related antitumor mechanisms of marine-derived agents

Zhixia Zhou, Qianqian Cao, Yujing Diao, Yin Wang, Linhai Long, Shoushi Wang, Peifeng Li

Front Pharmacol. 2022; 13: 1053556. Published online 2022 Dec 1. doi: 10.3389/fphar.2022.1053556

PMCID:: PMC9752855

Article PDF–2.4M

Select item 770569819.

The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing

Hai-Jun Hu, Xiu Liang, Hai-Lang Li, Chun-Ming Du, Jia-Li Hao, Huai-Yuan Wang, Jin-Fa Gu, Ai-Min Ni, Lan-Ying Sun, Jing Xiao, Jin-Qing Hu, Hao Yuan, Yan-Song Dai, Xiao-Ting Jin, Kang-Jian Zhang, Xin-Yuan Liu

Cell Death Dis. 2020 Nov; 11(11): 1022. Published online 2020 Nov 30. doi: 10.1038/s41419-020-03223-0

PMCID:: PMC7705698

Article PDF–18M

Select item 873888620.

Cry1Ac Protoxin Confers Antitumor Adjuvant Effect in a Triple-Negative Breast Cancer Mouse Model by Improving Tumor Immunity

Roberto Raúl Servin-Garrido, Damaris Ilhuicatzi-Alvarado, Ángel de Jesús Jiménez-Chávez, Leticia Moreno-Fierros

Breast Cancer (Auckl) 2022; 16: 11782234211065154. Published online 2022 Jan 5. doi: 10.1177/11782234211065154

PMCID:: PMC8738886

Article PDF–7.1M

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